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Deep insights. Simply put

Carefully curated. Deeply researched. Free of ads and shackles.

There are brilliant content producers with the finger on the pulse. So we won’t regurgitate the news just to keep up with the crowd, except if the news needs an urgent second opinion. And this is not a rarity. We take our time to see through commercial biases, and noodle on the nuances behind the headlines. Always in an easily digestible form. An individual human may be pear-shaped but is never bell-shaped - meaning, statistical evidence for whole populations may not fit well with you if you’re an edge case or working in extremes. Like many of our patients. While on the programme or alumni membership we’ll take the topics you ask us about and tailor what it means to those like you. And while we use AI tools to help us search and type faster, rest assured, we don’t rely on anyone except the experts.

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The Shingles Bell

The Shingles Bell

Shingles vaccination is a well-established way to reduce the risk and severity of shingles (Herpes zoster) and its often debilitating complications. In the last few years, multiple large population studies - now including “natural experiment” / quasi-randomised designs - have also reported a consistent association between shingles vaccination and a lower subsequent risk of dementia. Some of the strongest evidence suggests the effect may be greater in women.

These findings do not yet prove that shingles vaccines prevent Alzheimer’s disease (or dementia) directly, nor do they define the ideal timing for vaccination purely for neuroprotection. But the signal is now strong enough to justify a practical, evidence-aligned conclusion…

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Can You Train Your Brain to Boost Vaccine Response?
Foundational Health, Immunity Ranulf Crooke Foundational Health, Immunity Ranulf Crooke

Can You Train Your Brain to Boost Vaccine Response?

When mind meets immunity: why this matters

Missing a competition or event because of flu, feeling run down or watching your metrics dip after a jab, is a frustration many of us know well. We often treat the immune system as something we cannot consciously train, but recent studies hint that the way we think and feel could influence vaccine responses [1]. Imagine harnessing your mind to prime your body before the next vaccination. Yet the evidence is still young and nuanced. Before you start conjuring positivity at will, let’s unpack what one of the first human trials and the wider literature really show.

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Tapping the Vagus Nerve: Could a Gentle Electrical Pulse Fine-Tune Performance, Mood and Recovery?
Cognitive Health, Brain Health, Technology WellFounded team Cognitive Health, Brain Health, Technology WellFounded team

Tapping the Vagus Nerve: Could a Gentle Electrical Pulse Fine-Tune Performance, Mood and Recovery?

Why is the vagus nerve getting so much attention?

From challenging work situations to Strava leader-boards, people are evermore aware of ways to monitor their life-load and recover faster afterwards. At the centre of this sits the vagus nerve. Roughly 80% of its fibres carry information up to the brain, providing live “telemetry” on the body’s parasympathetic balance. Surgeons have long implanted electrodes around the cervical vagus to treat epilepsy and depression. Now pocket-sized gadgets promise to reach the same pathway through the skin of the outer ear or neck to stimulate the vagus nerve (transcutaneous VNS, or tVNS).

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