Deep insights. Simply put
Carefully curated. Deeply researched. Free of ads and shackles.
There are brilliant content producers with the finger on the pulse. So we won’t regurgitate the news just to keep up with the crowd, except if the news needs an urgent second opinion. And this is not a rarity. We take our time to see through commercial biases, and noodle on the nuances behind the headlines. Always in an easily digestible form. An individual human may be pear-shaped but is never bell-shaped - meaning, statistical evidence for whole populations may not fit well with you if you’re an edge case or working in extremes. Like many of our patients. While on the programme or alumni membership we’ll take the topics you ask us about and tailor what it means to those like you. And while we use AI tools to help us search and type faster, rest assured, we don’t rely on anyone except the experts.
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We geek out on:-
Preventive & therapeutic medicine
Leadership & relationships
Health-span research
Human Performance Science
Nutrition and 'Notrition' (fasting) and Nootrition (cognitive enhancement)
Sleep, Jetlag and circadian biology
Fitness & Physique
All things Psyche...
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Mitigating the cardiovascular risk of stress and depression
Do you worry about the long term consequences of sustained stress or depression on your health
Is it possible to mitigate the known risk of heart attacks due to chronic stress or depression 💔?
This could be highly relevant for many entrepreneurs and founders:
👉93% of founders in our analysis reported having felt overwhelmed with pressure or stress from responsibilities, circumstances or relationships 🤯
👉55% of founders were in the lowest quartile for cardiorespiratory fitness
Microplastics and Nanoplastics in Atheroma and Cardiovascular Events
In a recent publication in The New England Journal of Medicine, researchers have established a worrisome connection between the presence of microplastics and nanoplastics (MNPs) in atherosclerotic plaques and an increased risk of cardiovascular incidents. Highlighting MNPs as both enduring environmental contaminants and significant health risks, this study underscores the critical need for managing our exposure to these particles.
In this article Dr Andrew delves into the recent findings, providing insights on practical measures to minimize exposure and mitigate the health impacts of MNPs. Steering clear of alarmism, he advocates for a balanced, integrated approach that combines reducing MNP exposure with broader cardiovascular health strategies, including lifestyle changes and preventive healthcare.
Wonder Drug
Expedition Finse: The explorers return fresh from their recent adventures in Norway.
Exhausted but INSPIRED
A year ago today, our team accomplished an incredible feat by reaching the South Pole. The INSPIRE expedition taught us about the limits of human endurance, the power of resilience and teamwork, and how wearables enable studies into health and performance in the most extreme environments. We also discovered that women outperform men in certain aspects of hyper-endurance and learned invaluable lessons about teamwork and perseverance in the face of adversity.
Reflecting on this life-changing experience, and 40 year ambition, I realised how much it has impacted my approach to business, relationships, and life in general. Co-leading the INSPIRE expedition taught me a lot about how to be a better leader, doctor and carer, and face up to challenges head on, remaining optimistic. We have translated many of the INSPIRE findings into our WellFounded Health and performance programmes for Founders, CEOs and their investors. The results are most promising and illuminate how extreme environments research is specifically relevant to the work and lives of entrepreneurs.
I am deeply grateful for the lessons learned during this unforgettable journey and am grateful to be able to share them with you.
Sleep consistency vs duration: the underdog wins.
The emerging science of sleep has long emphasized the importance of sleep duration, typically recommending seven to nine hours per night for optimal health. However, the latest study published a few weeks ago in the journal Sleep offers a game-changing perspective. This isn't about clocking in more hours under the covers; it's about the rhythm and regularity of your sleep pattern.
Reduce hunger, boost mood and improve sleep with one simple tool: Time.
A study presented this week at the European Nutrition Conference by King’s Colege London highighted a study that sheds new light on the potential benefits of extending our morning fast that little bit further. The study, which is the largest of its kind outside of a clinical setting, has provided insightful findings on the benefits of eating within a 10-hour window and fasting for the remaining 14 hours. The results were presented at the European Nutrition Conference and drew upon data from users of the ZOE Health app.
Drop your blood glucose and improve your mood: A Simple Change to Combat the Risks of Prolonged Sitting
In the quest to mitigate the health risks associated with prolonged sitting, a recent study sheds light on the benefits of breaking up sedentary time with short, light-intensity walking breaks. It is already well reported that increased time sitting, above 6 to 8 hours per day of total sitting time and 3 to 4 hours per day of TV viewing time, are associated with greater risks of all-cause and cardiovascular deaths.
How to put on muscle: Why less might be more.
Blood flow restriction (BFR) training is a relatively new training method, but it has quickly gained popularity among athletes and fitness enthusiasts alike. This is because BFR has been shown to be very effective at increasing muscle strength and size, even when using light weights.
Mental Wellness for Founders and Building Resilience
While building WellFounded, we have seen first-hand how modern society profoundly influences our mental well-being, especially for entrepreneurs where the stresses and pressures can impact their entire business ecosystem. We don't build businesses in a vacuum and it is entirely normal that we bring with us the weight of modern stress and expectation. Our role at WellFounded is to assist where this becomes overwhelming and I think some of our founders might be surprised to learn how much this involves stress management and conflict resolution. However, we believe that if we better understand the effect that stress can have on our bodies' chemical balances and in turn our decision-making we can build healthy environments for both founders and their teams.
The Use of Cold Exposure to Promote Good Health
As WellFounded CEO, Dr Jack Kreindler and the INSPIRE 2022 team successfully completed their expedition to the South Pole earlier this year to explore the metabolic cost of sustained polar travel, those of us keeping a track of their journey through their social media channels were often in awe of just how much they were able to push their bodies each day in austere environments and freezing sub-zero temperatures. While not all of us will undertake an expedition in the South Pole in our lifetime, it is worth exploring the benefits of cold exposure and acclimatization in our day to day health outcomes.