Deep insights. Simply put
Carefully curated. Deeply researched. Free of ads and shackles.
There are brilliant content producers with the finger on the pulse. So we won’t regurgitate the news just to keep up with the crowd, except if the news needs an urgent second opinion. And this is not a rarity. We take our time to see through commercial biases, and noodle on the nuances behind the headlines. Always in an easily digestible form. An individual human may be pear-shaped but is never bell-shaped - meaning, statistical evidence for whole populations may not fit well with you if you’re an edge case or working in extremes. Like many of our patients. While on the programme or alumni membership we’ll take the topics you ask us about and tailor what it means to those like you. And while we use AI tools to help us search and type faster, rest assured, we don’t rely on anyone except the experts.
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We geek out on:-
Preventive & therapeutic medicine
Leadership & relationships
Health-span research
Human Performance Science
Nutrition and 'Notrition' (fasting) and Nootrition (cognitive enhancement)
Sleep, Jetlag and circadian biology
Fitness & Physique
All things Psyche...
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Microplastics and Nanoplastics in Atheroma and Cardiovascular Events
In a recent publication in The New England Journal of Medicine, researchers have established a worrisome connection between the presence of microplastics and nanoplastics (MNPs) in atherosclerotic plaques and an increased risk of cardiovascular incidents. Highlighting MNPs as both enduring environmental contaminants and significant health risks, this study underscores the critical need for managing our exposure to these particles.
In this article Dr Andrew delves into the recent findings, providing insights on practical measures to minimize exposure and mitigate the health impacts of MNPs. Steering clear of alarmism, he advocates for a balanced, integrated approach that combines reducing MNP exposure with broader cardiovascular health strategies, including lifestyle changes and preventive healthcare.
Blood Flow Restriction Training: Resistance training for time poor individuals
Blood Flow Restriction (BFR) training is making profound impacts on fitness routines worldwide, proving to be an adaptable and efficient method for achieving health and fitness goals amidst busy lifestyles and rehabilitation needs.
The technique employs strategic blood flow reduction to muscles during low-intensity exercises, enabling significant gains in muscle strength and size without the need for heavy lifting. Ideal for rehabilitation and those with limited gym access or time, BFR training is reshaping the way we think about fitness and recovery.
In this article, Dr Andrew explores the many benefits of this new approach to muscle development and rehabilitation, from enhanced muscle hypertrophy and strength to improved cardiovascular endurance and faster recovery times. Crucially, he will also guide you through the correct implementation of BFR training to ensure a safe and more effective workout.
Too much of a good thing? The latest on omega 3 for heart health
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued guidance urging caution over the potential link between omega-3 intake and atrial fibrillation, reigniting discussions around the health implications of these fatty acids.
Despite the concerns, the myriad of benefits of omega-3, particularly eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, continue to be a topic of interest for both cardiovascular health and beyond.
This article looks at the latest research and offers a comprehensive analysis of recent studies and trials, assessing the risks and benefits of omega-3, its impact on conditions such as atrial fibrillation, and its broader implications for public health recommendations.
Exhausted but INSPIRED
A year ago today, our team accomplished an incredible feat by reaching the South Pole. The INSPIRE expedition taught us about the limits of human endurance, the power of resilience and teamwork, and how wearables enable studies into health and performance in the most extreme environments. We also discovered that women outperform men in certain aspects of hyper-endurance and learned invaluable lessons about teamwork and perseverance in the face of adversity.
Reflecting on this life-changing experience, and 40 year ambition, I realised how much it has impacted my approach to business, relationships, and life in general. Co-leading the INSPIRE expedition taught me a lot about how to be a better leader, doctor and carer, and face up to challenges head on, remaining optimistic. We have translated many of the INSPIRE findings into our WellFounded Health and performance programmes for Founders, CEOs and their investors. The results are most promising and illuminate how extreme environments research is specifically relevant to the work and lives of entrepreneurs.
I am deeply grateful for the lessons learned during this unforgettable journey and am grateful to be able to share them with you.
Why is Maintaining Weight Loss so Hard?
Navigating Sleep and Brain Health: Insights from the UK Biobank Study
In the ever-evolving field of sleep research, the recent study published in the journal 'Sleep' titled, "Comprehensive assessment of sleep duration, insomnia, and brain structure within the UK Biobank cohort" marks a significant leap in understanding the complex interplay between sleep habits and brain health. Dr Andrew Crockett delves into this research and provides a critical analysis; shedding light on a subject of paramount importance for founders and professionals who grapple with the delicate balance between work demands and rest.
Musings on Music, the Mind and Medicine
Have you ever wondered why you feel a rush of excitement when your favourite pop song comes on the radio or feel a sense of calm when listening to a soothing classical piece? Dr. Jack Kreindler sheds light on the profound effects of music on our brains and bodies.
A passionate music enthusiast, rather than a music scientist, he delves into the fascinating world of music’s influence on human (and even non-human) biology, exploring the science behind why music affects us so deeply.
Drop your blood glucose and improve your mood: A Simple Change to Combat the Risks of Prolonged Sitting
In the quest to mitigate the health risks associated with prolonged sitting, a recent study sheds light on the benefits of breaking up sedentary time with short, light-intensity walking breaks. It is already well reported that increased time sitting, above 6 to 8 hours per day of total sitting time and 3 to 4 hours per day of TV viewing time, are associated with greater risks of all-cause and cardiovascular deaths.
A New Hope for Cancer
From hopeless in 1996 to Hope in AOH1996: The inspiring City of Hope Hospital’s own cancer research department has possibly achieved something that no other pharma company has managed since chemotherapy began in the mustard gas days. It’s an oral therapy candidate called AOH-1996 (not in humans yet).
James Kirkland's Quest to Extend Health span
“It’s much better to live till you’re 90 feeling you’re 50, than to live to be 180 feeling like you’re 180,”